Longevity Alzheimer’s Disease Blood Test
$299.00
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the gradual decline in cognitive function and memory loss. It is the most common cause of dementia, accounting for approximately 60-70% of cases. AD typically manifests in older adults, although early-onset forms can occur.
The hallmarks of Alzheimer’s disease include the accumulation of abnormal protein aggregates in the brain, namely beta-amyloid plaques and tau tangles. These pathological changes lead to neuronal damage and loss, disrupting communication between brain cells and impairing cognitive processes.
In Alzheimer’s disease (AD), abnormal accumulation of tau proteins within neurons is one of the key pathological hallmarks, alongside the deposition of beta-amyloid plaques. Tau proteins are essential for maintaining the structural integrity and function of neurons. However, in AD, tau proteins undergo abnormal changes, leading to the formation of insoluble aggregates known as neurofibrillary tangles (NFTs) inside neurons.
In Alzheimer’s disease, there is a decrease in the levels of acetylcholine due to the loss of cholinergic neurons in the brain. By inhibiting the enzyme cholinesterase, which breaks down acetylcholine, it is possible to maintain higher levels of acetylcholine in the brain, thereby improving communication between neurons and temporarily enhancing cognitive function.
Malondialdehyde (MDA) is a marker of oxidative stress and lipid peroxidation, which are processes implicated in the pathogenesis of Alzheimer’s disease (AD). Oxidative stress refers to an imbalance between the production of reactive oxygen species (ROS) and the body’s ability to neutralize them with antioxidants. In Alzheimer’s disease, increased oxidative stress leads to damage to cellular components, including lipids, proteins, and DNA, contributing to neuronal dysfunction and neurodegeneration.
Longevity Alzheimer’s Disease Blood Test: 8 Analytes tested: Amyloid Beta (Aβ) Peptides 42/40, Acetylcholinesterase (AChE), Choline, Malondialdehyde (MDA), Neurofilament Light Chain (NfL), Phosphorylated Tau 181 (p-T181), Phosphorylated Tau 217 (p-T217), Total Tau Proteins (t-tau)
Description
About the Test
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the gradual decline in cognitive function and memory loss. It is the most common cause of dementia, accounting for approximately 60-70% of cases. AD typically manifests in older adults, although early-onset forms can occur.
The hallmarks of Alzheimer’s disease include the accumulation of abnormal protein aggregates in the brain, namely beta-amyloid plaques and tau tangles. These pathological changes lead to neuronal damage and loss, disrupting communication between brain cells and impairing cognitive processes.
In Alzheimer’s disease (AD), abnormal accumulation of tau proteins within neurons is one of the key pathological hallmarks, alongside the deposition of beta-amyloid plaques. Tau proteins are essential for maintaining the structural integrity and function of neurons. However, in AD, tau proteins undergo abnormal changes, leading to the formation of insoluble aggregates known as neurofibrillary tangles (NFTs) inside neurons.
In Alzheimer’s disease, there is a decrease in the levels of acetylcholine due to the loss of cholinergic neurons in the brain. By inhibiting the enzyme cholinesterase, which breaks down acetylcholine, it is possible to maintain higher levels of acetylcholine in the brain, thereby improving communication between neurons and temporarily enhancing cognitive function.
Malondialdehyde (MDA) is a marker of oxidative stress and lipid peroxidation, which are processes implicated in the pathogenesis of Alzheimer’s disease (AD). Oxidative stress refers to an imbalance between the production of reactive oxygen species (ROS) and the body’s ability to neutralize them with antioxidants. In Alzheimer’s disease, increased oxidative stress leads to damage to cellular components, including lipids, proteins, and DNA, contributing to neuronal dysfunction and neurodegeneration.
Longevity Alzheimer’s Disease Blood Test: 8 Analytes tested: Amyloid Beta (Aβ) Peptides 42/40, Acetylcholinesterase (AChE), Choline, Malondialdehyde (MDA), Neurofilament Light Chain (NfL), Phosphorylated Tau 181 (p-T181), Phosphorylated Tau 217 (p-T217), Total Tau Proteins (t-tau)
