Longevity Nicotinamide Adenine Dinucleotide NAD/NADH Blood Test

$179.00

Nicotinamide adenine dinucleotide (NAD) and its reduced form, NADH, are coenzymes found in all living cells. They play crucial roles in various metabolic pathways, serving as carriers of electrons during cellular respiration and as cofactors for enzymes involved in redox reactions.

NAD is primarily involved in accepting and donating electrons in oxidation-reduction (redox) reactions, making it essential for energy production and metabolism. In its oxidized form (NAD+), it functions as an electron acceptor, while in its reduced form (NADH), it carries electrons to the electron transport chain in mitochondria, where they are used to generate ATP, the primary energy currency of cells.

In addition to its role in energy metabolism, NAD is also a substrate for enzymes involved in other important cellular processes, including DNA repair, gene expression, and cell signaling. NAD-dependent enzymes such as sirtuins, poly(ADP-ribose) polymerases (PARPs), and cyclic ADP-ribose synthases (CD38 and CD157) play key roles in regulating cellular homeostasis, stress response, and longevity.

The balance between NAD+ and NADH is tightly regulated within cells, and disruptions in this balance have profound effects on cellular function and health. Declines in NAD+ levels is associated with aging and age-related diseases, while increasing NAD+ levels through supplementation or activation of NAD+ biosynthetic pathways has been proposed as a potential strategy to promote healthy aging and improve metabolic health.

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About the Test

Nicotinamide adenine dinucleotide (NAD) and its reduced form, NADH, are coenzymes found in all living cells. They play crucial roles in various metabolic pathways, serving as carriers of electrons during cellular respiration and as cofactors for enzymes involved in redox reactions.

NAD is primarily involved in accepting and donating electrons in oxidation-reduction (redox) reactions, making it essential for energy production and metabolism. In its oxidized form (NAD+), it functions as an electron acceptor, while in its reduced form (NADH), it carries electrons to the electron transport chain in mitochondria, where they are used to generate ATP, the primary energy currency of cells.

In addition to its role in energy metabolism, NAD is also a substrate for enzymes involved in other important cellular processes, including DNA repair, gene expression, and cell signaling. NAD-dependent enzymes such as sirtuins, poly(ADP-ribose) polymerases (PARPs), and cyclic ADP-ribose synthases (CD38 and CD157) play key roles in regulating cellular homeostasis, stress response, and longevity.

The balance between NAD+ and NADH is tightly regulated within cells, and disruptions in this balance have profound effects on cellular function and health. Declines in NAD+ levels is associated with aging and age-related diseases, while increasing NAD+ levels through supplementation or activation of NAD+ biosynthetic pathways has been proposed as a potential strategy to promote healthy aging and improve metabolic health.