Tryptophan Metabolites & CoFactors Blood Test
$299.00
The kynurenine pathway (KP) is a crucial metabolic route for the catabolism of tryptophan, playing a significant role in various physiological and pathological processes. It is pivotal in producing several metabolites, including kynurenic acid and quinolinic acid, which have neuroprotective and neurotoxic properties, respectively. The balance of these metabolites is essential for maintaining brain health and preventing neurodegenerative diseases. Moreover, the KP is intimately linked to the immune system, with key enzymes like indoleamine 2,3-dioxygenase (IDO) being activated by pro-inflammatory cytokines, thereby regulating immune responses and inflammation. The pathway also contributes to the synthesis of nicotinamide adenine dinucleotide (NAD+), a vital coenzyme in cellular energy production and DNA repair. Dysregulation of the KP is associated with various conditions, including psychiatric disorders, autoimmune diseases, and cancer, making it a critical target for therapeutic interventions aimed at modulating tryptophan metabolism to treat these diseases and promote overall health.
9 Tryptophan Metabolites tested: Tryptophan, Kynurenine, Tryptophan/Kynurenine Ratio, Kynurenic Acid, Quinolinic Acid, NAD+/NADH, 5-Hydroxytryptophan (5-HTP), Serotonin, Melatonin
9 Co-Factors (Copper, Iron, Magnesium, Vitamin B2 (Riboflavin), Vitamin B6, Vitamin B9 (Folate), Methyl Vitamin B12, Vitamin D 25-OH, Zinc)
Description
The kynurenine pathway (KP) is a crucial metabolic route for the catabolism of tryptophan, playing a significant role in various physiological and pathological processes. It is pivotal in producing several metabolites, including kynurenic acid and quinolinic acid, which have neuroprotective and neurotoxic properties, respectively. The balance of these metabolites is essential for maintaining brain health and preventing neurodegenerative diseases. Moreover, the KP is intimately linked to the immune system, with key enzymes like indoleamine 2,3-dioxygenase (IDO) being activated by pro-inflammatory cytokines, thereby regulating immune responses and inflammation. The pathway also contributes to the synthesis of nicotinamide adenine dinucleotide (NAD+), a vital coenzyme in cellular energy production and DNA repair. Dysregulation of the KP is associated with various conditions, including psychiatric disorders, autoimmune diseases, and cancer, making it a critical target for therapeutic interventions aimed at modulating tryptophan metabolism to treat these diseases and promote overall health.
9 Tryptophan Metabolites tested: Tryptophan, Kynurenine, Tryptophan/Kynurenine Ratio, Kynurenic Acid, Quinolinic Acid, NAD+/NADH, 5-Hydroxytryptophan (5-HTP), Serotonin, Melatonin
9 Co-Factors (Copper, Iron, Magnesium, Vitamin B2 (Riboflavin), Vitamin B6, Vitamin B9 (Folate), Methyl Vitamin B12, Vitamin D 25-OH, Zinc)
